Complement-Fixation Reaction in Rinderpest. IV.

The Gomez Complement-fixation Reaction

Much has been done, but there is still much to be accomplished in the matter of tests for infection and immunity in leprosy. To be of help to the clinicians it is not sufficient for a test to be positive among the inmates of a leper asylum; it is necessary that it should work also in free surroundings where are met the doubtful cases, toward the' detection of which the greatest vigilance should...

The Complement-Fixation Reaction in Gonorrhœa

The complement-fixation reaction in gonorrhcea has not been applied widely like the Wassermann reaction in syphilis. There are three reasons for this : (1) A good antigen has been believed to be not easy to prepare. Specially selected strains of the bacterium have been considered necessary, and special preparations, ' toxins ' and lysates have been preferred to the simple bacterial suspensions ...

The Complement Fixation Reaction in Monkey Malaria

1. A specific complement fixation reaction test for Plasmodium knowlesi malaria in rhesus monkeys is reported with details involved in the preparation of the antigen and procedures employed in setting up the test. 2. It was found that specific complement-fixing antibodies appeared early in the course of the experimental disease and persisted during the course of the chronic infection. 3. The fi...

Indirect Complement Fixation in Foot-and-Mouth Disease

The Complement Fixation Reaction with Pneumococcus Capsular Polysaccharide

1. Complement is not fixed by immune aggregates resulting from the interaction of pneumococcus capsular polysaccharide and type-specific immune horse serum, although under proper conditions the substitution of immune rabbit serum gives positive results. 2. The negative results with immune horse serum are due to some poorly understood property of the specific antibodies rather than to some heter...